ABSTRACT This narrative review summarizes the main aspects underlying the new coronavirus SARS-CoV-2, its epidemiology, pathophysiology, pointing to differences of SARS-CoV-2 main receptors ACE2, in terms of expression and the amount of soluble ACE2 in the circulation of children, men and women, and also in those with risk factors such as the smoke
Top-down sequencing in proteomics has come of age owing to continuous progress in LC-MS.With their high resolution and broad mass range, Quadrupole Time-of-Flight (Q-ToF) hybrid mass spectrometers equipped with electrospray ionisation source and tandem MS capability by collision-induced dissociation (CID) can be employed to analyse intact proteins
Abstract Background Mitochondria are thought to have evolved from eubacteria-like endosymbionts; however, the origin of the mitochondrion remains a subject of debate.In this study, we investigated the phenomenon of chimerism in mitochondria to shed light on the origin of these organelles by determining which species played a role in their formation
Abstract Background Globally, preterm birth is the leading cause of neonatal and under-five children mortality.Sub-Saharan African (SSA) accounts for the majority of preterm birth and death following its complications.Despite this, there is limited evidence about the pooled prevalence and associated factors of preterm birth at SSA level using natio